1 Scope
This standard specifies the determination of six polyether antibiotics residues in milk and milk powder through LC-MS-MS method.
This standard is applicable to the determination of lasalocid, monensin, nigericin, salinomycin, narasin and madubamycin ammonium residues in liquid milk (including raw milk, pure milk and skimmed milk) and milk powder (including pure milk powder, skimmed milk powder and baby formula milk powder).
Method detection limit of this standard: the detection limits of lasalocid, monensin, nigericin, salinomycin, narasin and madubamycin ammonium in milk are 0.2μg/L, and the detection limits in milk powder are l.6μg/kg.
2 Normative References
The following standards contain provisions which, through reference in this text, constitute provisions of this standard. For dated reference, subsequent amendments to (excluding correction to), or revisions of, any of these publications do not apply. However, all parties coming to an agreement according to this standard are encouraged to study whether the latest edition of these documents is applicable. For undated references, the latest edition of the normative document is applicable to this standard.
GB/T 6379.1 "Accuracy (Trueness and Precision) of Measurement Methods and Results-Part 1: General Principles and Definitions" (GB/T 6379.1-2004, ISO 5725-1:1994, IDT)
GB/T 6379.2 "Accuracy (Trueness and Precision) of Measurement Methods and Results-Part 2: Basic Method for the Determination of Repeatability and Reproducibility of a Standard Measurement Method" (GB/T 6379.2-2004, ISO 5725-2:1994, IDT)
GB/T 6682 "Water for Analytical Laboratory Use-Specification and Test Methods" (GB/T 6682-2008, ISO 3696:1987, MOD)
Foreword I
1 Scope
2 Normative References
3 Principle
4 Reagents and Materials
5 Instruments and Equipment
6 Sample Preparation and Preservation
7 Determination Method
8 Result Calculation
9 Precision
Appendix A (Informative) Multiple Reaction Monitoring (MRM) Chromatogram of Standard Substances
Appendix B (Informative) Recovery
